Status:

UNKNOWN

Plaque Stability and Metabolomics in Coronary Heart Disease

Lead Sponsor:

Shaanxi Provincial People's Hospital

Conditions:

Coronary Artery Disease

Eligibility:

All Genders

18-90 years

Brief Summary

At present, the investigators don't know the relationship between plaque stability and the metabonomics changes. In the present study, investigators will evaluate the plaque stability by intravascular...

Eligibility Criteria

Inclusion

  • Patients who diagnosed with stable coronary heart disease and evaluated for plaque stability by IVUS will be recruited.

Exclusion

  • renal insufficiency with serum creatinine \> 20 mg/L;
  • regnant/lactating women, or the women receive hormone replacement therapy in premenopausal or postmenopausal;
  • patients have a history of abusing alcohol or other drugs in the past two years, active hepatitis, cirrhosis;
  • endocrine abnormalities without therapy (diabetic ketoacidosis, thyroid disease, etc.);
  • The body's inflammatory disease, rheumatoid arthritis, osteoarthritis, ulcerative bowel disease, systemic lupus erythematosus (sle), etc.), myositis/myopathy, cancer;
  • Dilated cardiomyopathy, valvular heart disease, persistent atrial fibrillation;
  • patients recently injured;(8)Other researchers don't agree to join this study.

Key Trial Info

Start Date :

July 1 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 31 2024

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT05270330

Start Date

July 1 2021

End Date

July 31 2024

Last Update

March 8 2022

Active Locations (1)

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Shaanxi Provincial People's Hospital

Xi'an, Shaanxi, China, 710061