Status:

COMPLETED

Non-invasive Assessment to Predict Tolerance to Fluid Removal on Intermittent Kidney Replacement Therapy

Lead Sponsor:

Centre hospitalier de l'Université de Montréal (CHUM)

Collaborating Sponsors:

The Kidney Foundation of Canada

Conditions:

Acute Kidney Injury

Chronic Kidney Disease Stage 5 on Dialysis

Eligibility:

All Genders

18+ years

Brief Summary

This prospective cohort study aim to investigate the ability of multiple types of assessments including 1) the modified Venous Excess Ultrasound (VExUS) assessment, 2) non-invasive estimation of absol...

Detailed Description

Background: Fluid accumulation and intra-dialytic hypotensive events (IDHE) are independently associated with worse prognosis in patients undergoing intermittent kidney replacement therapy (IKRT), bo...

Eligibility Criteria

Inclusion

  • Adult patient ≥18 year-old
  • Hospitalized at the CHUM in the intensive care unit (ICU) or general ward
  • Receiving or planned ≥3x/week IKRT treatments
  • Planned on-line hemodiafiltration (HDF) or hemodialysis (HD) sessions with ≥1L of fluid removal per session

Exclusion

  • Planned hospital discharge, death, or transition to comfort care within 48 hours according to the attending physician
  • End of active care (awaiting hospital discharge)

Key Trial Info

Start Date :

March 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 17 2024

Estimated Enrollment :

93 Patients enrolled

Trial Details

Trial ID

NCT05270759

Start Date

March 1 2022

End Date

September 17 2024

Last Update

September 19 2024

Active Locations (1)

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1

Centre Hospitalier de l'Université de Montréal

Montreal, Quebec, Canada, H2X 0C1