Status:

UNKNOWN

A Multi-center RWS of Perampanel as an add-on Treatment for Epileptic Seizures in Chinese Children

Lead Sponsor:

Beijing Children's Hospital

Conditions:

Epilepsy

Eligibility:

All Genders

2-12 years

Brief Summary

This study is a multi-center, real-word clinical trial. The purpose of this study is to evaluate the safety and effectiveness of perampanel as an add-on treatment for epileptic seizure, and to find th...

Detailed Description

This is a multi-center, prospective, observational study. Subjects who meet all of the inclusion and none of the exclusion criteria will be received perampanel. Baseline seizure counts (frequency) dat...

Eligibility Criteria

Inclusion

  • Age ≥2y, ≤12y;
  • Within 3 months before taking perampanel, the frequency of epileptic seizures was ≥1 time/month on average;
  • 1-3 kinds of AEDs have been used, and the optimal dose and course of treatment have been reached, but the effect is not good. Perampanel is used as an additional treatment.

Exclusion

  • Patients who have participated in other researches on antiepileptic drugs or medical devices;
  • Inaccurate or unreliable clinical records according to the judgment of participating doctors;
  • When the database is closed, the expected follow-up time is less than 6 months.

Key Trial Info

Start Date :

July 2 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 31 2022

Estimated Enrollment :

1000 Patients enrolled

Trial Details

Trial ID

NCT05274035

Start Date

July 2 2021

End Date

July 31 2022

Last Update

March 25 2022

Active Locations (5)

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Page 1 of 2 (5 locations)

1

Beijing Children's Hospital, Capital Medical University

Beijing, Beijing Municipality, China, 100045

2

Wuhan Children's Hospital, Tongji Medical College of Huazhong University of Science and Technology

Wuhan, Hubei, China, 430015

3

XuZhou Children's Hospital

Xuzhou, Jiangsu, China, 221002

4

Jinan Children's Hospital

Jinan, Shandong, China, 250022