Status:
COMPLETED
Efficacy of Preoperative Radiotherapy for Non-responder Patients After Neoadjuvant Chemotherapy
Lead Sponsor:
Istanbul Breast Society
Conditions:
Breast Neoplasms
Radiotherapy; Complications
Eligibility:
FEMALE
18-70 years
Brief Summary
Neoadjuvant chemotherapy (NACT) is widely used for locally advanced breast cancer cases. As the key factor is to achieve pathologic complete response (pCR), several physicians tried administering radi...
Detailed Description
Patients who received NACT were enrolled on the study depending on their order of admission. NACT regimen was 4 cycles of anthracycline and cyclophosphamide with 12 cycles of taxane based regimen. Tra...
Eligibility Criteria
Inclusion
- American Joint Committee on Cancer (AJCC) clinical T1-3
- Biopsy proven N+
- Non-metastatic (M0)
- Patients who are planned to receive adjuvant radiotherapy at initial evaluation
- Patients who are candidate for neoadjuvant chemotherapy
- Patients who did not achieved clinical complete response after neoadjuvant chemotherapy
Exclusion
- AJCC clinical T4
- AJCC Clinical N-
- AJCC Clinical M1
- Patients who achieved clinical complete response after neoadjuvant chemotherapy
- Patients who did not consent to have neoadjuvant radiotherapy
Key Trial Info
Start Date :
January 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2022
Estimated Enrollment :
37 Patients enrolled
Trial Details
Trial ID
NCT05274594
Start Date
January 1 2017
End Date
January 1 2022
Last Update
March 10 2022
Active Locations (1)
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1
Istanbul Breast Society
Istanbul, Turkey (Türkiye), 34093