Status:

COMPLETED

Impact on Risk Stratification of Overlap Syndrome Phenotype in Patients With E1784K Mutation in SCN5A

Lead Sponsor:

Centre Hospitalier Universitaire de la Réunion

Conditions:

Long QT Syndrome

Brugada Syndrome

Eligibility:

All Genders

12+ years

Brief Summary

In patients expressing the SCN5A-E1784K mutation (Glu1784Lys), cardiovascular risk is difficult to define as the stratification of these patients is challenging. From our experience, major cardiovascu...

Detailed Description

Study design: This study will compare the occurrence of MCE between patients with overlap syndrome phenotype and patients with a single phenotype (whether Brugada syndrome or Long QT syndrome type 3) ...

Eligibility Criteria

Inclusion

  • genotype E1784K (glu1784lys) in SCN5A gene

Exclusion

  • none

Key Trial Info

Start Date :

April 5 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 20 2024

Estimated Enrollment :

47 Patients enrolled

Trial Details

Trial ID

NCT05274646

Start Date

April 5 2022

End Date

March 20 2024

Last Update

August 5 2025

Active Locations (1)

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1

CHU de La Réunion

Saint-Pierre, France, Reunion, 97440