Status:
RECRUITING
Utilization of a Videoscope in Periodontal Regeneration
Lead Sponsor:
University of Illinois at Chicago
Conditions:
Chronic Periodontitis
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Clinical and preclinical studies confirm that regeneration of supporting tissues of teeth lost due to periodontal disease can be achieved using the principles of minimally invasive surgery (MIS). Alth...
Eligibility Criteria
Inclusion
- • Individual must be between the age of 18 and 70 years of age
- ASA I or II systemically healthy subjects
- Individuals presenting with at least 1 single or multirooted tooth with residual, isolated, interproximal bony defect with probing depths (PD) ≥ 6 mm, clinical attachment loss (CAL) ≥ 6mm, bleeding upon probing (BOP), and ≥ 2mm width of attached gingiva (WAG)
- Radiographic evidence of interproximal alveolar bone loss, on existing (\< 2 years old) dental radiographs of diagnostic quality taken at the COD
- Vital tooth or previous root canal therapy with no signs/symptoms of pathology
- Individuals with plaque scores ≤ 20%
- English speaking subjects (Individual must be willing to follow all the study requirements and participate in the study procedures in its entirety and read, understand the informed consent form)
Exclusion
- Individuals not referred from the Predoctoral Periodontics Student Clinics
- Uncontrolled systemic disorders such as hypertension, heart disease, bleeding disorders, metabolic bone diseases, autoimmune disorders, etc., that may influence cellular/healing status
- Diabetics
- Current smokers
- Individual less than 18 years of age
- Individuals with non-isolated, interproximal PD ≥ 4 mm extending to the facial/buccal and/or palatal/lingual tooth surfaces
- Teeth with Grade 2 or 3 mobility
- Teeth with metal restorations such as a porcelain fused to metal crown (due to scattering of radiographic images)
- Intrabony defects on dental implants
- Individual who take medications known to affect host immunity or periodontal tissues (ex. steroids, antibiotics, phenytoin, etc.) in the previous 6 months
- Individuals on chronic anti-platelet/anti-coagulant therapy
- Oral pathologies other than periodontal disease (ex. periapical lesions of non-periodontal origin)
- Subjects who may be pregnant based on a positive pregnancy test
- Non-English speaking individuals
Key Trial Info
Start Date :
May 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT05275192
Start Date
May 1 2022
End Date
December 31 2026
Last Update
December 13 2024
Active Locations (1)
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1
University of Illinois, Chicago, College of Dentistry, Periodontics
Chicago, Illinois, United States, 60612