Status:

RECRUITING

ZNN Bactiguard Retrograde Femoral Nails PMCF Study

Lead Sponsor:

Zimmer Biomet

Conditions:

Femoral Fracture

Eligibility:

All Genders

18+ years

Brief Summary

Post-market clinical follow-up (PMCF) study to confirm the safety, performance, and clinical benefits of the intra-medullary retrograde femoral nail Zimmer Natural Nail (ZNN) Bactiguard (implants and ...

Detailed Description

The objective of this prospective PMCF study is to collect data to confirm safety, performance and clinical benefits of the Zimmer Natural Nail (ZNN) Bactiguard Retrograde Femoral Nail (implants and i...

Eligibility Criteria

Inclusion

  • Patients must be 18 years or older.
  • Patient must have a femoral fracture (open, closed, monolateral or bilateral) requiring surgical intervention and be eligible for fixation by intramedullary nailing. Patients with delayed treatment (initial treatment by external fixation due to swelling / high energy trauma followed by definitive treatment by intramedullary nail) can also be included.
  • Patient has been or is scheduled to be treated with the ZNN Bactiguard System Retrograde Femoral Nail.
  • Patient must be able and willing to complete the protocol required follow-up.
  • Patient must have a signed EC approved consent.
  • Patients capable of understanding the surgeon's explanations and following his instructions.

Exclusion

  • Skeletally immature patients
  • A medullary canal obliterated by a previous fracture or tumor
  • Bone shaft having excessive bow or a deformity
  • Lack of bone substance or bone quality, which makes stable seating of the implant impossible
  • All concomitant diseases that can impair the operation, functioning or the success of the implant
  • Insufficient blood circulation
  • Infection
  • Patient is unwilling or unable to give consent.
  • Patient is a vulnerable subject (prisoner, mentally incompetent or unable to understand what participation to the study entails, alcohol/drug addiction, known to be pregnant or breast feeding).
  • Patient anticipated to be non-compliant and/or likely to have problems with maintaining follow-up program (e.g. patient with no fixed address, long distance, plans to move during course of study).
  • Not expected to survive the duration of the follow-up program

Key Trial Info

Start Date :

October 23 2023

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2027

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT05276674

Start Date

October 23 2023

End Date

December 1 2027

Last Update

December 4 2024

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Hospital Universitario Ntra. Sra. de Candelaria

Santa Cruz de Tenerife, Tenerife, Spain, 38010

2

Leeds General Infirmary

Leeds, United Kingdom, LS1 3EX

3

Manchester Royal Infirmary

Manchester, United Kingdom

4

Stepping Hill Hospital

Stockport, United Kingdom

ZNN Bactiguard Retrograde Femoral Nails PMCF Study | DecenTrialz