Status:

UNKNOWN

Household Study of COVID-19, Influenza and RSV Burden, Transmission Dynamics and Viral Interaction in South Africa

Lead Sponsor:

National Institute for Communicable Diseases, South Africa

Collaborating Sponsors:

Perinatal HIV Research Unit of the University of the Witswatersrand

University of Witwatersrand, South Africa

Conditions:

SARS-CoV-2 Infection

Influenza

Eligibility:

All Genders

Up to 99 years

Brief Summary

The study aims to characterize the community burden (including the clinical features) and transmissibility of SARS-CoV-2 within the context of a functional antibody response. In addition,the study wil...

Detailed Description

Background and justification: On 31 December 2019, the World Health Organization (WHO) was alerted to a cluster of pneumonia cases of unknown etiology in patients in Wuhan City, Hubei Province of Chin...

Eligibility Criteria

Inclusion

  • Households/individuals that consent to participate to the study; and that are planning to reside in the selected community for the duration of the study.
  • Provide at least one serum sample in the intensive follow up period, for individuals five years and older and
  • Households should have at least 3 or more.

Exclusion

  • Households that:
  • Non-eligible households will be households that were not randomly selected, that were selected but did not consent to participate to the study or, that have \>20% of household members who do not consent for inclusion in the study.

Key Trial Info

Start Date :

July 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 31 2022

Estimated Enrollment :

1200 Patients enrolled

Trial Details

Trial ID

NCT05277298

Start Date

July 1 2020

End Date

December 31 2022

Last Update

March 14 2022

Active Locations (2)

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Page 1 of 1 (2 locations)

1

MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), Bushbuckridge, South Africa

Agincourt, Mpumalanga, South Africa, 1256

2

Perinatal HIV Research

Klerksdorp, North West, South Africa, 4538