Status:
RECRUITING
Dextromethorphan for Treatment of Postoperative Pain
Lead Sponsor:
Nathanael Heckmann
Conditions:
Post-operative Pain
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
A Randomized, Placebo-Controlled Study to Evaluate the Efficacy of Perioperative Dextromethorphan compared to Placebo for the Treatment of Postoperative Pain
Detailed Description
There is extensive preclinical evidence that dextromethorphan has an analgesic effect in patients with pain of traumatic origin. The primary objective is to of this study is to evaluate the efficacy o...
Eligibility Criteria
Inclusion
- Main
- Patients Age ≥18 planning to undergo total knee arthroplasty
- ASA classes I - III
- Main
Exclusion
- BMI ≥ 35
- History opioid abuse
- History of intractable vomiting after previous surgery
Key Trial Info
Start Date :
September 15 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
160 Patients enrolled
Trial Details
Trial ID
NCT05278494
Start Date
September 15 2022
End Date
December 31 2026
Last Update
December 12 2024
Active Locations (1)
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1
Keck School of Medicine of USC
Los Angeles, California, United States, 90033