Status:

COMPLETED

HF Patients With LVADs Being Treated With SGLT2i

Lead Sponsor:

University of Chicago

Conditions:

Heart Failure With Reduced Ejection Fraction

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The main purpose of this study is to observe outcomes of sodium-glucose co-transporter 2 inhibitors (SGLT2i) in heart failure (HF) patients with left ventricular assist devices (LVAD).

Detailed Description

The exact mechanism of cardiovascular benefit from SGLT2i continues to be the source of further research. The investigators hypothesize that heart failure patients with LVADs will similarly benefit fr...

Eligibility Criteria

Inclusion

  • LVAD implantation
  • Have not already been prescribed management with an SGLT2i
  • Estimated glomerular filtration rate (eGFR) ≥ 30 milliliters(ml)/minute(min)/1.73 meter(m)2
  • Age ≥ 18 years-old
  • Able to provide informed consent

Exclusion

  • Diagnosis of Type 1 diabetes mellitus
  • eGFR \< 30 ml/min/1.73 m2
  • Age \< 18 years-old

Key Trial Info

Start Date :

September 8 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 31 2025

Estimated Enrollment :

32 Patients enrolled

Trial Details

Trial ID

NCT05278962

Start Date

September 8 2022

End Date

August 31 2025

Last Update

September 9 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Chicago

Chicago, Illinois, United States, 60637