Status:
UNKNOWN
Epinephrine Infusion for Prophylaxis Against Maternal Hypotension During Cesarean Delivery
Lead Sponsor:
Kasr El Aini Hospital
Conditions:
Postspinal Hypotension
Cesarean Delivery
Eligibility:
FEMALE
18-40 years
Phase:
PHASE4
Brief Summary
Maternal hypotension after spinal block is a common complication after subarachnoid block in this population. The incidence of maternal hypotension is nearly 60% when prophylactic vasopressors are not...
Detailed Description
Upon arrival to the operating room, the patient will be in supine position with left uterine displacement using a wedge below the right buttock. Routine monitoring will be applied (electrocardiography...
Eligibility Criteria
Inclusion
- full-term singleton pregnant women
- American society of anesthesiologist-physical status I or II,
- scheduled for elective cesarean delivery
Exclusion
- Patients with uncontrolled cardiac morbidities (patients with tight valvular lesion, impaired contractility with ejection fraction \< 50%, heart block, and arrhythmias),
- hypertensive disorders of pregnancy,
- peripartum bleeding,
- coagulation disorders (patients with INR \>1.4 and or platelet count \< 80000 /dL) or
- any contraindication to regional anesthesia,
- and baseline systolic blood pressure (SBP) \< 100 mmHg
Key Trial Info
Start Date :
March 21 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2022
Estimated Enrollment :
276 Patients enrolled
Trial Details
Trial ID
NCT05279703
Start Date
March 21 2022
End Date
August 1 2022
Last Update
August 26 2022
Active Locations (1)
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1
Kasr Alaini Hospital
Cairo, Egypt, 11562