Status:
ACTIVE_NOT_RECRUITING
Sickle Cell Disease (SCD) Bone Pain Study
Lead Sponsor:
University of California, Davis
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Doris Duke Charitable Foundation
Conditions:
Sickle Cell Disease
Sickle Cell Anemia
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
A prospective study to determine how low bone mineral density and/or vertebral compression fractures associate with pain in adults with sickle cell disease
Detailed Description
The investigators hypothesize that adults with sickle cell disease (SCD) and low bone density and/or vertebral compression fractures on a dual X-ray absorptiometry (DXA) scan (adjusted for age, sex, S...
Eligibility Criteria
Inclusion
- Age 18-80 years with SCD (any genotype, confirmed by hemoglobin electrophoresis or high performance liquid chromatography)
- Ability to provide written informed consent
- Ability to lay on a DXA scanner
- Negative urine pregnancy test for women of childbearing potential at study entry
Exclusion
- Pregnant women
- Adults unable to consent
- Individuals who are not yet adults (infants, children, teenagers)
- Prisoners
- Hospitalizations (any cause) within 2 weeks of study entry
Key Trial Info
Start Date :
November 3 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 31 2026
Estimated Enrollment :
53 Patients enrolled
Trial Details
Trial ID
NCT05283148
Start Date
November 3 2022
End Date
July 31 2026
Last Update
August 24 2025
Active Locations (1)
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1
UC Davis Comprehensive Cancer Center
Sacramento, California, United States, 95817