Status:
UNKNOWN
Research About Impact of HPV Integration on the Prognosis of Women With Persistent HR-HPV Infection
Lead Sponsor:
Fujian Maternity and Child Health Hospital
Conditions:
HPV Infection
LSIL, Low-Grade Squamous Intraepithelial Lesions
Eligibility:
FEMALE
Brief Summary
Clinically, patients with persistent HR-HPV infection for more than 18 months or HR-HPV infection with CIN2 + need regular colposcopic biopsy to assess the outcome and progression of the disease. A to...
Detailed Description
This study aims to: 1) determine the association between HPV integration and natural outcome in women with persistent HR-HPV infection. 2) determine the prognostic value of different HPV integration s...
Eligibility Criteria
Inclusion
- Non pregnant people with sexual history；
- Persistent infection of the same type of HR-HPV for more than 18 months or HR-HPV infection with CIN2 +;
- No history of previous surgery at the cervical site.
- Asexual life, no vaginal medication or flushing before 72 hours of sampling.
Exclusion
- Within 8 weeks after pregnancy or postpartum.
- Patients with history of genital tract tumor.
- History of HPV vaccination.
- Previous history of hysterectomy, cervical surgery, pelvic radiotherapy Historical.
- In recent one month, she has received genital tract infection, HPV or other STDs treatment related to the infection of mycoplasma.
- Use antibiotics or vaginal microecological improvement products in recent 1 month.
Key Trial Info
Start Date :
January 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2024
Estimated Enrollment :
1000 Patients enrolled
Trial Details
Trial ID
NCT05283239
Start Date
January 1 2022
End Date
December 31 2024
Last Update
November 18 2023
Active Locations (11)
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1
Fujian Maternity and Child Health Hospital
Fuzhou, Fujian, China, 350001
2
Mindong Hospital of Ningde City
Ningde, Fujian, China, 352000
3
Ningde Municipal Hospital of Ningde Normal University
Ningde, Fujian, China, 352100
4
The First Hospital of Putian City
Putian, Fujian, China, 351100