Status:
COMPLETED
Comparative Study Between the Prophylactic Intravenous Administrations of Acetaminophen vs Dexamethasone vs Pethidine Regarding the Incidence of Shivering Induced by Single Shot Spinal Anesthesia in the Orthopedic Surgeries of the Lower Limbs
Lead Sponsor:
Ain Shams University
Conditions:
Shivering
Eligibility:
All Genders
20-55 years
Phase:
PHASE4
Brief Summary
Single Shot Spinal anesthesia (SSSA) is associated with considerable perioperative shivering and can be challenging to treat. Some pharmacologic agents like N-methyl d-aspartate receptor antagonists, ...
Detailed Description
Aim of this study is to compare between the prophylactic intravenous administrations of acetaminophen vs dexamethasone vs pethidine regarding the incidence of shivering induced by single shot spinal a...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists physical status (ASA) I or II.
- Both sexes.
- Age ranging from 20 to 55 years old.
- Body weight ranging from 60 to 100 kilograms.
- Receiving Single Shot Spinal anesthesia.
- Scheduled for orthopedic surgeries of the lower limb.
Exclusion
- Patient's refusal.
- Allergy to local anesthetics or any of the studied drugs.
- Patients with significant cognitive dysfunction.
- Duration of surgery more than 120 min.
- Patients with hypo- or hyperthyroidism.
- An initial body temperature \>38.0 or \<36.0 degree Celsius.
- Receiving vasodilators, or medications likely to alter thermoregulation.
- Pregnancy.
- Sensory blockade level reaching T4 or higher.
- Obesity (BMI \> 35 kg/m2).
Key Trial Info
Start Date :
July 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2022
Estimated Enrollment :
130 Patients enrolled
Trial Details
Trial ID
NCT05284409
Start Date
July 1 2022
End Date
October 1 2022
Last Update
January 29 2025
Active Locations (1)
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1
Ain Shams University Hospitals
Cairo, Egypt, 1181