Status:
RECRUITING
HD-tDCS Combined With Circadian Rhythm Reconstruction and Micro Expression Changes on Consciousness Recovery in Patients With Chronic Disturbance of Consciousness
Lead Sponsor:
First Affiliated Hospital of Zhejiang University
Conditions:
Disorder of Consciousness
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The circadian rhythm characteristics of sleep cycle and neuroendocrine in patients with chronic disorder of consciousness show different degrees of disorder, and the relationship between this disorder...
Detailed Description
The sleep status (\> 24 hours) of patients with chronic disturbance of consciousness was recorded with the revised coma recovery scale revised (CRS-R) and Polysomnography (PSG). The sleep cycle of pat...
Eligibility Criteria
Inclusion
- Patients with diagnosis of disorder of consciousness
- Stable vital signs
- Good coordination, less spontaneous activity
- No anti-epileptic and sedative drugs taken within prior 24 hours
- The family members volunteered and signed the informed consent
Exclusion
- locked-in syndrome
- Diseases and factors that may affect the judgment of brain function, such as metabolic diseases, poisoning, shock, etc.
- There are contraindications to MRI scanning, such as the presence of metal implants in the body
- Contraindications treated by transcranial direct current stimulation
Key Trial Info
Start Date :
July 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2024
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT05285124
Start Date
July 1 2021
End Date
December 1 2024
Last Update
June 4 2024
Active Locations (1)
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1
First Affiliated Hospital,Zhejiang University
Hanzhou, Zhejiang, China, 310003