Status:
UNKNOWN
Macro- and Microcirculation Crosstalk in Brain-damaged Patients Under Anesthesia or in Intensive Care
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
INSERM UMR-942, Paris, France
LMS Polytechnique
Conditions:
Brain Injury
Eligibility:
All Genders
18+ years
Brief Summary
In patients with severe brain injury, maintenance and control of blood pressure is at the very first point in the management strategy, whether in anesthesia or in intensive care. In order to restore c...
Detailed Description
In patients with severe brain injury, maintenance and control of blood pressure is at the primary focus of the management strategy in both anesthesia and intensive care. In order to restore cerebral p...
Eligibility Criteria
Inclusion
- Adult patients (≥ 18 years old)
- With brain damage
- Benefiting from general anesthesia or resuscitation justifying the placement of an arterial catheter and monitoring of cardiac output
- With hypotension or arterial hypertension requiring intravenous administration of a vasoactive agent to meet the target cerebral perfusion pressure (CPP) of 60-70 mmHg
- Not subject to a measure of legal protection (tutorship/curatorship)
- Patients informed and having expressed their non-objection to participation in this research, or, where applicable, a person of trust / family member / relative of the patient who is unable to express her or his agreement
Exclusion
- Patients under the age of 18
- Pregnant woman
- Patient without affiliation to a social security scheme
- Patient, or, where applicable, person of trust / family member / relative of the patient unable to express her or his agreement, opposed to participation in the study
- Patient subject to a legal protection measure
- Patient benefiting from the State medical assistance (AME) program
Key Trial Info
Start Date :
June 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2025
Estimated Enrollment :
85 Patients enrolled
Trial Details
Trial ID
NCT05285514
Start Date
June 1 2023
End Date
July 1 2025
Last Update
April 27 2023
Active Locations (1)
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1
AP-HP, Lariboisière Hospital, Department of Anesthesiology and Intensive Care
Paris, France, 75010