Status:
TERMINATED
Post-operative Pain Control With Acetaminophen and Ibuprofen After Functional Endoscopic Sinus Surgery
Lead Sponsor:
University of Illinois at Chicago
Conditions:
Chronic Rhinosinusitis (Diagnosis)
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The safest and most effective post-operative pain control regimen after functional endoscopic sinus surgery (FESS) has been the subject of persistent research. This prospective study will compare post...
Detailed Description
The safest and most effective post-operative pain control regimen after functional endoscopic sinus surgery (FESS) has been the subject of persistent debate and research for many years. The main reaso...
Eligibility Criteria
Inclusion
- Males and females ≥18 years of age.
- Patients of the PI (Dr. Joe) scheduled for sinus surgery at UI Health.
- Patients with CRS defined as greater than 12 weeks of 2 of the 4 following symptoms: nasal obstruction/congestion, mucopurulent discharge (nasal or postnasal), facial pain/pressure, or decreased/loss of smell + endoscopic/radiographic evidence of disease.
- CRS patients with or without nasal polyps.
- Patients who are COVID-19 negative.
- Patients that understand the purpose and procedures of the study and who agree to participate.
- Patients who have the capacity to consent autonomously.
Exclusion
- Males and females \< 18 years of age.
- Patients of the PI (Dr. Joe) who are not scheduled for sinus surgery at UI Health.
- Patients who do not have CRS.
- Patients who have allergies to acetaminophen, ibuprofen, and related non-steroidal anti-inflammatory drugs (NSAIDS).
- Patients with kidney or liver dysfunction, cirrhosis, metabolic deficiencies, inflammatory bowel disease, peptic ulcer disease, chronic malnutrition, who have had a previous skull base surgery, or who are currently undergoing cancer treatment.
- Woman who are pregnant or breastfeeding will be excluded.
- Patients with a history of drug and/or narcotic abuse will be excluded.
- COVID-19 positive patients.
- Patients who are not able to understand the purpose and procedures of the study and who do not wish to participate.
- Patients that do not have the capacity to consent autonomously.
Key Trial Info
Start Date :
July 29 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2023
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05287217
Start Date
July 29 2022
End Date
June 30 2023
Last Update
May 20 2025
Active Locations (1)
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1
University of Illinois at Chicago, Department of Otolaryngology-Head and Neck Surgery
Chicago, Illinois, United States, 60612