Status:

COMPLETED

Bi-Polar Radio-Frequency and Electrical Muscle Stimulation for Symptoms of Mixed Urinary Incontinence (MUI)

Lead Sponsor:

InMode MD Ltd.

Conditions:

Urinary Incontinence

Eligibility:

FEMALE

20-75 years

Phase:

NA

Brief Summary

The objective of this trial is to evaluate the safety and efficacy of the combined FormaV and VTone Applicators for Symptoms of Mixed Urinary Incontinence. Eligible subjects will receive 3 treatments...

Eligibility Criteria

Inclusion

  • Signed informed consent to participate in the study.
  • Female subjects, 20 to 75 years of age at the time of enrolment with moderate to severe symptoms of MUI, who had scored a relative even proportion of urge and stress subscale scores on the Medical, Epidemiologic, and Social Aspects of Aging Urinary Incontinence (MESA) Questionnaire completed at the screening assessment
  • General good health confirmed by medical history and examination of the treated area.
  • The patients should be willing to comply with the study procedure and schedule, including the follow up visit, and will refrain from using any other aesthetic treatment methods for the last 6 months and during the entire study period.

Exclusion

  • 5 Exclusion criteria
  • Pacemaker or internal defibrillator, or any other active electrical implant anywhere in the body.
  • Patients who have vaginal metal piercing, or intrauterine contraceptive device (IUCD or ICD or coil or any other device made of metal).
  • Permanent implant in the treated area such as metal plates and screws, silicone implants or an injected chemical substance, unless deep enough in the periostal plane.
  • Current or history of cancer, or premalignant condition in the treatment area.
  • Severe concurrent conditions, such as cardiac disorders, epilepsy, uncontrolled hypertension, and liver or kidney diseases.
  • Pregnancy and nursing.
  • Impaired immune system due to immunosuppressive diseases such as AIDS and HIV, or use of immunosuppressive medications.
  • Patients with history of diseases stimulated by heat, such as recurrent Herpes Simplex in the treatment area, may be treated only following a prophylactic regimen.
  • Poorly controlled endocrine disorders, such as diabetes or thyroid dysfunction.
  • Any active condition in the treatment area, such as sores, psoriasis, eczema, and rash.
  • History of skin disorders, keloids, abnormal wound healing, as well as very dry and fragile skin.
  • History of bleeding coagulopathies or use of anticoagulants in the last 10 days.
  • Any surgery in treated area within 3 months prior to treatment.
  • Simultaneous participation in another investigator drug or device study or completion of the follow-up phase for the primary endpoint of any previous study less than 30 days prior to the first evaluation in this study.
  • Six months delay is required if other recent treatments like light, CO2 laser or RF were performed on the same area.
  • Use of Isotretinoin (Accutane®) within 6 months prior to treatment.
  • Simultaneously participating in another investigator drug or device study or has completed the follow-up phase for the primary endpoint of any previous study less than 30 days prior to the first evaluation in this study.
  • As per the practitioner's discretion, refrain from treating any condition that might make it unsafe for the patient

Key Trial Info

Start Date :

April 4 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 30 2022

Estimated Enrollment :

31 Patients enrolled

Trial Details

Trial ID

NCT05287490

Start Date

April 4 2021

End Date

July 30 2022

Last Update

August 11 2022

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Advanced Women's Care of the Lowcountry, PC

Bluffton, South Carolina, United States, 29910

2

Lisa M Jukes MD

West Lake Hills, Texas, United States, 78746