Status:

UNKNOWN

E-cadherin and Integrin Alpha v Beta 1 in Vitiligo

Lead Sponsor:

Kasr El Aini Hospital

Conditions:

Vitiligo

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

The purpose of this clinical trial is to study the effect of Narrow Band UVB on E-cadherin and integrin alpha v beta 1 as representatives of adhesion molecules in non-segmental vitiligo in a trial to ...

Eligibility Criteria

Inclusion

  • All clinically diagnosed cases of non-segmental vitiligo .
  • Patients with VIDA +1 or more (new/expanding lesions active in time period of 6-12 months ago) will be included in the trial. Activity of vitiligo will be evaluated through Vitiligo Disease Activity (VIDA) Score.

Exclusion

  • Patients who have stable disease at the time of study i.e. no progression of existing disease or appearance of new lesions in the last six months.
  • Patients receiving treatment for vitiligo 3 months prior to the study.
  • Patients with contraindications for phototherapy.
  • Patients with current/history of any systemic and/or dermatological diseases affecting the immune system as autoimmune diseases and malignancy.

Key Trial Info

Start Date :

June 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2022

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT05287776

Start Date

June 1 2019

End Date

December 1 2022

Last Update

March 18 2022

Active Locations (1)

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Kasr El Ainy university hospital, Faulty of medicine,Cairo university

Cairo, El Manial, Egypt, 11956