Status:
UNKNOWN
Developing Prediction Models for Allograft Failure After Liver Transplantation
Lead Sponsor:
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Collaborating Sponsors:
University of California, Los Angeles
University Hospital Padova
Conditions:
Liver Transplant Disorder
Eligibility:
All Genders
18+ years
Brief Summary
Prompt identification of allograft failure (AF) is highly desirable to address patients to liver retransplantation, in order to maximize results and preserve patients safety. Recently, sophisticated ...
Detailed Description
Background. During the last decade, the expansion of the donor pool by using extended criteria donors (ECD) grafts and those after cardiac death (DCD) have redrawn the attention around allograft failu...
Eligibility Criteria
Inclusion
- Adult recipients (≥18 years)
- First transplant (retransplant cases should be enrolled if the first transplant is part of the study)
- DBD grafts
- DCD grafts (controlled and uncontrolled)
- DBD and DCD grafts managed by perfusion machines
- Living donor grafts (both left lobe and right lobe grafts) transplanted into adult recipients.
- Split liver grafts (both left lobe and right lobe grafts) transplanted into adult recipients.
Exclusion
- Combined grafts (e.g., liver-kidney, liver-heart, liver-pancreas, multi-visceral grafts)
- Domino grafts
- Heterotopic grafts
- Double grafts
- Recipients undergoing liver transplants for cholangiocarcinoma and colorectal liver metastases
Key Trial Info
Start Date :
April 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 1 2024
Estimated Enrollment :
5000 Patients enrolled
Trial Details
Trial ID
NCT05289609
Start Date
April 1 2022
End Date
April 1 2024
Last Update
March 21 2022
Active Locations (18)
Enter a location and click search to find clinical trials sorted by distance.
1
Dumont-UCLA Transplant and Liver Cancer Centers, Department of Surgery, David Geffen School of Medicine at UCLA
Los Angeles, California, United States, 90095
2
Department of Transplant, Mayo Clinic Florida
Jacksonville, Florida, United States, 32224
3
Division of Organ Transplantation, Department of Surgery, University of Massachusetts Memorial Hospital, University of Massachusetts
Worcester, Massachusetts, United States, 01655
4
Transplantation Center, Digestive Disease and Surgery Institute, Cleveland Clinic
Cleveland, Ohio, United States, 44195