Status:
COMPLETED
Impact of Pea, Lentil and Oat Flour Particle Size on Glycemic Response in Healthy Adults
Lead Sponsor:
University of Toronto
Collaborating Sponsors:
University of Saskatchewan
Saskatchewan Food Industry Development Center
Conditions:
Malnutrition; Diabetes
Malnutrition; Protein
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
The study looks at the comparative effects of food products made with pea, lentil, and oat flour of various particle sizes on postprandial glycemic response, appetite and food intake, and amino acid r...
Detailed Description
A total of 60 participants (30 males, 30 females) will take part in this study at the University of Toronto. Twenty participants will be recruited to each one of three trials (pea, lentil or oat) and ...
Eligibility Criteria
Inclusion
- 18-45 years of age
- BMI 18.5-29.9 kg/m2
- Willing to maintain habitual diet, physical activity pattern, and body weight throughout the trial.
- Willing to maintain current dietary supplement use throughout the trial.
- Willing to abstain from alcohol consumption for 24h prior to all test visits.
- Willing to avoid vigorous physical activity for 24h prior to all test visits.
- Understanding the study procedure and willing to provide informed consent to participate in the study and authorization to release relevant protected health information to the study investigator.
Exclusion
- Smoking
- Thyroid problems
- Previous history of cardiovascular disease, diabetes, liver or kidney disease, inflammatory bowel disease, celiac disease, short bowel syndrome, a malabsorptive syndrome, pancreatitis, gallbladder or biliary disease.
- Presence of a gastrointestinal disorder or surgeries within the past year.
- Known to be pregnant or lactating.
- Unwillingness or inability to comply with the experimental procedures and to follow our safety guidelines.
- Allergies to peanuts and nuts.
- Known intolerances, sensitivity or allergy to any ingredients in the study products: pea flour, lentil flour, oat flour and whole wheat flour.
- Regular breakfast skipping (consumes breakfast less than 5 days a week)
- Extreme dietary habits (i.e Atkins diet, very high protein diets, etc.) or restrained eaters, identified by a score of ≥ 11 on the Eating Habits Questionnaire
- Uncontrolled hypertension (systolic blood pressure \> 140 mm Hg or diastolic blood pressure \> 90 mm Hg) as defined by the average blood pressure measured at screening.
- Weight gain or loss of at least 10lbs in previous three months.
- Excessive alcohol intake (more than 2 drinks per day or more than 9 drinks per week).
- Consuming prescription or non-prescription drug, herbal or nutritional supplements known to affect blood glucose or that could affect the outcome of the study as per investigator's judgment.
Key Trial Info
Start Date :
April 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2023
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05291351
Start Date
April 1 2022
End Date
December 31 2023
Last Update
July 5 2024
Active Locations (1)
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1
Department of Nutritional Sciences
Toronto, Ontario, Canada, M5S 3E2