Status:
NOT_YET_RECRUITING
Are Mast Cells Involved in Autoinflammatory Diseases
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Collaborating Sponsors:
Institut Imagine
Conditions:
Autoinflammatory Disease
FMF
Eligibility:
All Genders
18+ years
Brief Summary
Autoinflammatory diseases (AID) are caused by innate immunity dysregulation. AID pathophysiology is only partly understood, especially in the case of unclassified AID. Mast cells (MC) are innate immun...
Detailed Description
Autoinflammatory diseases (AID) are caused by innate immunity dysregulation and characterized by recurrent bouts of fever, frequently associated with digestive, articular or cutaneous symptoms, and so...
Eligibility Criteria
Inclusion
- Patients \>18 years old with Auto-inflammatory diseases already followed up at the CeRéMAIA (french national reference center for autoinflamamtory diseases and AA amyloidosis) of Tenon hospital and included in the JIRcohorte
- Healthy adult controls, age- and sex-matched with MAI patients, and controls with mastocytosis, an immuno-inflammatory disease.
- Subject affiliated to or entitled to a social security scheme
- Collection of the patient's or healthy control's non-opposition
Exclusion
- Subjects unable to answer questions or express themselves
- Subjects who do not speak French
- Subject deprived of liberty or under legal protection.
Key Trial Info
Start Date :
March 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2026
Estimated Enrollment :
590 Patients enrolled
Trial Details
Trial ID
NCT05292768
Start Date
March 1 2022
End Date
October 1 2026
Last Update
March 23 2022
Active Locations (1)
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1
Service de Médecine Interne
Paris, France, 75020