Status:

RECRUITING

Uninterrupted Direct-acting Oral Anticoagulation in Patients Undergoing Transradial Percutaneous Coronary Procedures

Lead Sponsor:

Hospital Universitario La Fe

Conditions:

Coronary Artery Disease

Bleeding

Eligibility:

All Genders

Phase:

PHASE4

Brief Summary

Up to 20-30% of patients who are candidates for direct oral anticoagulation (DOAC) present with concomitant ischemic heart disease and often require coronary angiography with or without percutaneous c...

Detailed Description

The study design is an investigator-initiated, single-arm, open-label, pilot study in patients treated with DOAC undergoing trans-radial percutaneous coronary procedures. Because of the exploratory n...

Eligibility Criteria

Inclusion

  • Patients under anticoagulation with DOAC and any indication for diagnostic or therapeutic trans-radial percutaneous coronary procedures. At least 25% of the population undergoing PCI will be included.

Exclusion

  • Aged \< 18 years
  • Cardiogenic shock
  • Major active bleeding at the time of the procedure
  • Use of mechanical circulatory support
  • Chronic total occlusions
  • Pre-planned vascular access different from radial artery access (i.e. femoral, brachial, ulnar)
  • Inability to provide informed consent
  • Unable to understand and follow study-related instructions or unable to comply with study protocol
  • Currently participating in another trial
  • Pregnant women

Key Trial Info

Start Date :

January 20 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 20 2024

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT05292846

Start Date

January 20 2022

End Date

April 20 2024

Last Update

January 26 2024

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Humanitas Research Hospital

Rozzano, Milan, Italy, 20089

2

Hospital del Mar

Barcelona, Spain

3

Hospital La Paz

Madrid, Spain

4

Hospital Universitario y Politécnico La Fe

Valencia, Spain, 46026