Status:

COMPLETED

Improving Antibiotic Stewardship for Children With Respiratory Illness Presenting to Village Health Workers in Uganda

Lead Sponsor:

University of North Carolina, Chapel Hill

Collaborating Sponsors:

Thrasher Research Fund

Conditions:

Respiratory Infections in Children

Eligibility:

All Genders

2-5 years

Phase:

NA

Brief Summary

This is a stepped wedge, cluster randomized study of a clinical algorithm that includes point-of-care C-reactive protein testing to inform antibiotic treatment decisions by village health workers for ...

Eligibility Criteria

Inclusion

  • Age 2 months-5 years
  • Evaluated by a study VHW in one of the participating villages in Bugoye sub-county for acute respiratory illness defined as the following: fever (documented (temperature \> 38°C) or subjective fever in the last seven days) AND fast breathing (respiratory rate \> 30) OR cough

Exclusion

  • Age \> 5 years or \< 2 months at time of presentation
  • Guardian not present to provide consent

Key Trial Info

Start Date :

November 2 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 30 2022

Estimated Enrollment :

1280 Patients enrolled

Trial Details

Trial ID

NCT05294510

Start Date

November 2 2021

End Date

May 30 2022

Last Update

August 4 2022

Active Locations (1)

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1

Bugoye Health Center III

Bugoye, Kasese District, Uganda