Status:

NOT_YET_RECRUITING

co Ihibtory Receptor in Preeclampsia

Lead Sponsor:

Assiut University

Conditions:

Pre-Eclampsia

Eligibility:

FEMALE

Phase:

PHASE4

Brief Summary

Preeclampsia is a form of hypertensive pregnancy disorder with multiorgan involvement. It is characterized by new-onset hypertension and proteinuria after 20 weeks' gestation in a woman whose blood pr...

Detailed Description

T lymphocytes, as well as their regulatory subpopulations could possibly possess a part in PE . The changes in T cell subsets that may be seen in preeclampsia include low Treg activity, a shift toward...

Eligibility Criteria

Inclusion

  • total of 41 women in third trimester pregnancy complicated with PE showing:
  • Blood pressure ≥140/90 mmHg and
  • Proteinuria ≥300 mg/24 hours with or without
  • Edema in pregnant woman after week 20 of gestation (American Congress of Obstetricians and Gynecologists (ACOG2013) (17)

Exclusion

  • B-Exclusion criteria • Patients with autoimmune, acute inflammatory, and chronic diseases, are excluded from the study.

Key Trial Info

Start Date :

January 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

November 4 2025

Estimated Enrollment :

82 Patients enrolled

Trial Details

Trial ID

NCT05294952

Start Date

January 1 2025

End Date

November 4 2025

Last Update

February 5 2024

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