Status:
COMPLETED
Accelerated Transcranial Magnetic Stimulation (TMS) for Smoking Cessation in People Living With HIV/AIDS (PLWHA)
Lead Sponsor:
Gopalkumar Rakesh
Collaborating Sponsors:
National Cancer Institute (NCI)
Conditions:
Hiv
Tobacco Smoking
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
To demonstrate whether four sessions of TBS improves attentional bias and craving in PLWHA smokers compared to four sessions of sham stimulation. We hypothesize 4 sessions of TBS to the left DLPFC wil...
Detailed Description
The proposed pilot study seeks to explore modulation of attentional bias and tobacco craving in PLWHA with one session of adequately dosed theta burst stimulation (TBS). Results of this trial will spu...
Eligibility Criteria
Inclusion
- Potential participants will be
- Patients enrolled in the Bluegrass Clinic
- 18-60 years of age
- Male or female gender
- Able to read, understand and communicate in English
- Willing to adhere to the general rules of the Bluegrass Clinic/SMARTClinic/Beyond Birth Clinic
- Willing and able to abstain from drug use other than Suboxone
- Exhaled breath on day of study carbon monoxide (CO) \< 5 ppm
- Stabilized on maintenance buprenorphine if having comorbid opioid use disorder.
Exclusion
- Positive pregnancy test for females, traumatic brain injury, history of seizure disorder, history of or current diagnosis of schizophrenia, intracranial metal shrapnel.
- Previous adverse effect with TMS.
- Sub-threshold consistency while performing behavioral tasks.
- Failure to show baseline attentional bias to smoking versus neutral cues.
Key Trial Info
Start Date :
April 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 31 2024
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT05295953
Start Date
April 1 2022
End Date
July 31 2024
Last Update
October 22 2025
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
245 Fountain Court
Lexington, Kentucky, United States, 40513
2
University of Kentucky
Lexington, Kentucky, United States, 40513