Status:

RECRUITING

Validation of the REMINDER Dementia Risk Reduction Program

Lead Sponsor:

University of Coimbra

Collaborating Sponsors:

Fundação para a Ciência e a Tecnologia

Conditions:

Healthy Aging

Risk Reduction

Eligibility:

All Genders

60-75 years

Phase:

NA

Brief Summary

Until now, neuropsychological interventions aimed to optimize cognitive function and to have functional impact in individuals at risk of AD (MCI patients) were scarce in validity studies. While some R...

Detailed Description

The overarching tenet of this project is that, by providing a manualized multidomain intervention - REMINDER - that engages at risk individuals in the aims of this protocol, it can have a significant ...

Eligibility Criteria

Inclusion

  • Age 60 or older
  • CAIDE dementia risk score \>8
  • Cognitive function: absence of significant cognitive impairment as per the Addenbrooke's Cognitive Examination-REVISED
  • Free of physical disabilities that preclude participation in the study
  • Willing to complete all study-related activities for 12 weeks

Exclusion

  • Mild cognitive impairment or dementia;
  • Presence of any neurological event in their medical history that could compromise actual cognition.
  • Presence of any severe psychiatric disorder (mild depressive and anxiety symptoms meet inclusion criteria).
  • Unability to travel to the site where the sessions will be delivered (if so randomization will be circumscribed between the experimental harm REMINDER online and the control group.
  • Illiteracy

Key Trial Info

Start Date :

April 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2026

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT05296980

Start Date

April 1 2022

End Date

October 1 2026

Last Update

May 8 2024

Active Locations (1)

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1

Faculty of Psychology and Educational Sciences

Coimbra, Portugal, 3002-115