Status:

COMPLETED

Longitudinal Monitoring of Microsurgical Socket Augmentation Healing With Ultrasonography

Lead Sponsor:

University of Michigan

Collaborating Sponsors:

Delta Dental Foundation

Conditions:

Healing Wound

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this study is to assess healing after tooth extraction with simultaneous socket augmentation (bone grafting during the same appointment as the extraction) when the surgeon uses a surgic...

Detailed Description

After a tooth is extracted, a hole is left in the bone called a socket. During the first year of healing after a tooth extraction, there may be up to 60% loss of bone volume at the site. Loss of bone ...

Eligibility Criteria

Inclusion

  • At least 18 years of age
  • Single maxillary or mandibular hopeless tooth (a maxillary or mandibular anterior tooth or premolar) planned for extraction due to periapical pathology with a minimum ≥2 mm of the size of the periapical radiolucency shown on a peri-apical film.
  • The patient is planned for implant restoration for the hopeless tooth
  • The study site allows for implant placement with or without additional bone augmentation procedures after the healing
  • Adequate edentulous space for the final restoration on the implant

Exclusion

  • Current smokers or quit smoking less than 6 months
  • Major or uncontrolled medical conditions, e.g. poorly controlled diabetes mellitus (HbA1c \>8.0%, uncontrolled systemic disease or condition known to alter bone metabolism, e.g. osteoporosis, osteopenia, hyperparathyroidism, Paget's disease, etc.
  • Pregnancy, breast-feeding, could be pregnant or planning to become pregnant in the next 4 months (self-reported)
  • Taking medications known to modify bone metabolism (i.e. bisphosphonates, corticosteroids, hormone replacement therapy)

Key Trial Info

Start Date :

March 22 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 21 2023

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT05297071

Start Date

March 22 2022

End Date

July 21 2023

Last Update

February 28 2024

Active Locations (1)

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1

University of Michigan School of Dentistry

Ann Arbor, Michigan, United States, 48109