Status:

COMPLETED

The SleepWell Study - Chronotherapeutic Intervention to Improve Sleep Following ACS

Lead Sponsor:

Columbia University

Collaborating Sponsors:

National Institute on Aging (NIA)

Conditions:

Sleep Disturbance

Insomnia

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This two-phase pilot study will test the feasibility of a "combined chronotherapy" (CC) intervention consisting of morning bright light therapy (BLT) and evening blue light blocking (BLB), administere...

Detailed Description

Survivors of acute medical events often experience psychological distress including post-traumatic stress disorder (PTSD). The goal of this project is to conduct preliminary testing of a chronotherape...

Eligibility Criteria

Inclusion

  • Patients will be eligible for PHASE A if they meet the following criteria
  • 18 years of age or older,
  • can write, speak and read English,
  • provider and patient confirmed ACS,
  • ACS event occurred within the past 3 months, and
  • presence of insomnia symptoms based on the Insomnia Symptoms Questionnaire, or frequently (3-4 times per week) or always (5-7 times per week) experiencing short sleep duration of 6 hours or less per night.

Exclusion

  • severe disabling chronic medical and/or psychiatric comorbidities determined on a case-by-case basis that prevent safe or adequate participation;
  • deemed unable to comply with the protocol (either self-selected or indicated during screening that s/he/they could not complete all requested tasks). This includes, but is not limited to, patients with a level of cognitive impairment indicative of dementia, patients with current alcohol or substance abuse, and patients with severe mental illness (e.g., schizophrenia);
  • unavailable for follow-up for reasons such as terminal illness and imminent plans to leave the United States (as we have migrant or mobile patients due to their citizenship and work issues);
  • Non-English speaking;
  • Lack of reliable phone or e-mail access;
  • History of bipolar disorder (manic episode can be triggered by BLT) or positive screen for bipolar disorder based on the Mood Disorder Questionnaire;
  • Eye disease including glaucoma or retinopathy (BLT contraindications);
  • Blindness;
  • Night shift work schedules;
  • taking any anti-depressant or anti-anxiety medications; and
  • taking other medications that increase sensitivity to light (by self-report).
  • Patients will be eligible for PHASE B if they meet the following criteria:
  • Inclusion Criteria:
  • 18 years of age or older,
  • can write, speak and read English or Spanish,
  • provider and patient confirmed ACS,
  • ACS event occurred within the past 3 months, and
  • presence of insomnia symptoms based on the Insomnia Symptoms Questionnaire, or frequently (3-4 times per week) or always (5-7 times per week) experiencing short sleep duration of 6 hours or less per night.

Key Trial Info

Start Date :

April 18 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 26 2024

Estimated Enrollment :

19 Patients enrolled

Trial Details

Trial ID

NCT05299723

Start Date

April 18 2022

End Date

June 26 2024

Last Update

January 7 2025

Active Locations (1)

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CUIMC

New York, New York, United States, 10032