Status:
COMPLETED
Vagus Nerve-guided Robotic-assisted Splenectomy and Azygoportal Disconnection
Lead Sponsor:
Northern Jiangsu People's Hospital
Conditions:
Cirrhosis
Hypertension
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study aimed to evaluate whether vagus nerve-guided robotic-assisted splenectomy and azygoportal disconnection is effective and safe, and to determine whether a reduction in the incidence of posto...
Detailed Description
After successful screening the cases of cirrhosis of liver irrespective of the etiology who have non tumor portal vein thrombosis will be enrolled. The baseline parameter will be recorded and the pati...
Eligibility Criteria
Inclusion
- A clinical, radiological or histologic diagnosis of cirrhosis of any etiology
- Splenomegaly with secondary hypersplenism
- Bleeding portal hypertension
- No evidence of portal vein system thrombosis by ultrasound evaluation and angio-CT
- Informed consent to participate in the study
Exclusion
- Delayed gastric emptying
- Diarrhea
- Hepatocellular carcinoma or any other malignancy,
- Hypercoagulable state other than the liver disease related
- DRUGS- oral contraceptives, anticoagulation or anti-platelet drugs.
- Child - Pugh C
- Recent peptic ulcer disease
- History of Hemorrhagic stroke
- Pregnancy.
- Uncontrolled Hypertension
- Human immunodeficiency virus (HIV) infection
Key Trial Info
Start Date :
April 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 31 2023
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05300516
Start Date
April 1 2022
End Date
July 31 2023
Last Update
December 21 2023
Active Locations (1)
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1
Clinical Medical College, Yangzhou University
Yangzhou, Jiangsu, China, 225001