Status:
RECRUITING
Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty
Lead Sponsor:
University of California, San Francisco
Collaborating Sponsors:
MedStar Georgetown University Hospital
Conditions:
Urethral Stricture, Male
Eligibility:
MALE
18+ years
Phase:
PHASE3
Brief Summary
Patients undergoing buccal urethroplasty will often have significant post-operative oral pain from the graft site. Various graft harvest techniques and methods for post-harvest hemostasis including gr...
Detailed Description
This is a blinded, randomized, controlled trial following patients undergoing buccal urethroplasty (see criteria). This study will aim to assess three established anesthetic protocols for oral pain co...
Eligibility Criteria
Inclusion
- Men, age 18 or older
- Undergoing anterior urethroplasty with buccal grafting
- Able to consent
Exclusion
- Taking chronic opiates for pain
- Diagnosis of chronic pain
- Prior buccal urethroplasty
- Vulnerable population (e.g. prisoner)
- Renal dysfunction or allergy preventing NSAID use
- Liver dysfunction or allergy preventing Tylenol use
- Medical allergy to local anesthetic
- Medical allergy to Peridex/Magic Mouthwash
- NYHA Class III/IV
- Hematologic condition that excludes patient from surgery
- Post-operative complication resulting in inpatient stay
- Anesthetic complication
- No buccal site surgical complication
Key Trial Info
Start Date :
February 15 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2026
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05300685
Start Date
February 15 2022
End Date
March 1 2026
Last Update
October 24 2025
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
University of California San Francisco
San Francisco, California, United States, 94143
2
MedStar Urology
Washington D.C., District of Columbia, United States, 20037