Status:

COMPLETED

Safety of Genexol PM and Carboplatin as First-line Therapy in Ovarian Cancer

Lead Sponsor:

Seoul National University Hospital

Collaborating Sponsors:

Samyang Biopharmaceuticals Corporation

Conditions:

Ovarian Cancer

Eligibility:

FEMALE

18+ years

Brief Summary

To evaluate the safety profile of Genexol PM combination with carboplatin for patients with newly diagnosed ovarian cancer. We hypothesized Genexol PM can be safely administered to newly diagnosed ova...

Eligibility Criteria

Inclusion

  • Age over 18
  • Patients consented to participate
  • Pathologically diagnosed ovarian cancer FIGO stage IC-IVB
  • ECOG 0-2
  • Patients with an expected survival of 3 months or more

Exclusion

  • History of paclitaxel or carboplatin hypersensitivity
  • Inadequate bone marrow function (Neutrophil\<1500/mm3, Platelet \<100,000/mm3)
  • Pregnancy or breast-feeding state
  • Metachronous or synchronous malignancy
  • Galactose intolerance, Lapp Lactase deficiency, or glucose-galactose malabsorption patients with genetic problems
  • Other patients who were judged difficult to be included in this investigation by the investigator in charge

Key Trial Info

Start Date :

October 19 2015

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2022

Estimated Enrollment :

600 Patients enrolled

Trial Details

Trial ID

NCT05300828

Start Date

October 19 2015

End Date

December 31 2022

Last Update

June 26 2023

Active Locations (1)

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1

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Ajou University School of Medicine

Suwon, South Korea