Status:

RECRUITING

Aromatherapy Inhaler Use for HSCT Distress

Lead Sponsor:

Stanford University

Conditions:

Cancer Distress

Cancer Coping

Eligibility:

All Genders

19+ years

Phase:

NA

Brief Summary

The purpose of this research is to evaluate aromatherapy inhaler use and how it may impact cancer distress and coping by patients in the first few days after hematopoietic stem cell transplant (HSCT).

Detailed Description

Phase 1: Transplant Day +1, +2, or +3. Phase 2: Washout Day: Standard of care (SOC) pharmacological intervention only. Phase 3: Transplant Day +3, +4, or +5). Study Completion: Transplant Day +4, +5, ...

Eligibility Criteria

Inclusion

  • Autologous and Allogeneic patients admitted to E1 for planned HSCT
  • Patients with hematologic malignancies requiring HSCT
  • No allergies to lavender or peppermint essential oils
  • Must have received chemotherapy during preparative regimen (single or multi-agent regimen)
  • Adult patient over 18 years of age
  • Able to speak, read, and comprehend English
  • Willing and capable of providing informed consent

Exclusion

  • Patients admitted for Chimeric Antigen Receptor T cell (CART) infusion
  • Patients receiving a transplant for a germ cell tumor diagnosis
  • Unexpected/unplanned admission (e.g., neutropenic fever, confusion, clinical deterioration)
  • Immune effector cell-associated neurotoxicity syndrome (ICANS) grade 1 through 4
  • History of scleroderma
  • History of atrial fibrillation
  • Known history of G6PD deficiency
  • Allergic to lavender or peppermint essential oils
  • Pediatric patient 18 years of age or less
  • Unable to speak, read, and comprehend English
  • Unwilling or incapable of providing informed consent

Key Trial Info

Start Date :

June 16 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2026

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT05302583

Start Date

June 16 2025

End Date

March 1 2026

Last Update

September 3 2025

Active Locations (1)

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Stanford University

Stanford, California, United States, 94305