Status:
UNKNOWN
Comparison Between Letrozole and Mifepristone in Medical Termination of First Trimester Miscarriages
Lead Sponsor:
Calcutta National Medical College and Hospital
Conditions:
Miscarriage
Eligibility:
FEMALE
18-40 years
Phase:
PHASE3
Brief Summary
Prospective interventional study where participants with non-viable pregnancy at 1st trimester will be randomized into two arms, one group will receive conventional treatment with oral mifepristone fo...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA :
- Women older than 18years who will give consent regarding medical management of missed abortion
- First trimester pregnancy (gestational age less than equal to 12weeks) with missed abortion confirmed by ultrasonography
- Hemoglobin level more than 12mg/dl
- EXCLUSION CRITERIA :
- Hemodynamically unstable patient
- Abnormalities in blood tests including complete blood count (CBC), prothrombin time(PT), internationalised normalized ratio(INR) and fibrinogen
- History or clinical evidence of any thromboembolic impairment or deep venous thrombosis
- Having intra-uterine device
- Present or previous use of corticosteroids
- History of any malignancy
- Existing cardiovascular disease contraindicating misoprostol
Exclusion
Key Trial Info
Start Date :
May 5 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2024
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT05304273
Start Date
May 5 2022
End Date
May 1 2024
Last Update
September 6 2023
Active Locations (1)
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1
Calcutta National Medical College and Hospital
Kolkata, West Bengal, India, 700014