Status:
UNKNOWN
Effects of S-ketamine and Continuous Iliac Fascia Space Block on Perioperative Neurological Cognitive Impairment and Postoperative Rehabilitation in Elderly Patients With Hip Fracture
Lead Sponsor:
Yangzhou University
Conditions:
Hip Fractures
Eligibility:
All Genders
65-85 years
Phase:
NA
Brief Summary
Elderly patients with hip fracture are older and have a high incidence of perioperative complications. the postoperative recovery of elderly patients with hip fracture is affected by hemodynamic insta...
Detailed Description
With the advent of the aging society, the incidence of hip fracture in elderly patients is increasing year by year, and the incidence of perioperative neurological cognitive impairment (PND) is increa...
Eligibility Criteria
Inclusion
- Clinical diagnosis of hip fracture
- Aged 65 or above
- ASA Ⅰ-Ⅲ
- No mental and nervous system diseases
- No pathological fractures, such as bone tumor, bone tuberculosis, osteomyelitis, etc
- No puncture site infection
- No hospital stay for more than 48 hours after operation
Exclusion
- Patients with severe cardiac, hepatic and renal dysfunction before operation
- Long-term use of analgesics, sedatives and alcoholism
- Patients with respiratory tract management difficulties (modified Ma's score is IV)
- Previous neuropsychiatric diseases such as severe cerebrovascular, Alzheimer's disease, epilepsy and Parkinson's disease
- Previous history of intracranial surgery or craniocerebral injury
- Severe vision, hearing, language impairment or other reasons unable to communicate
- Allergic or contraindicated to ropivacaine or non-steroidal anti-inflammatory drugs (NSAID)
- Emergency surgery or trauma patients.
Key Trial Info
Start Date :
March 26 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 31 2023
Estimated Enrollment :
108 Patients enrolled
Trial Details
Trial ID
NCT05304559
Start Date
March 26 2022
End Date
January 31 2023
Last Update
March 31 2022
Active Locations (1)
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1
Affiliated Hospital of Yangzhou University
Yangzhou, China