Status:
UNKNOWN
Telocytes in Umbilical Cord of Patients With and Without Pre-eclampsia
Lead Sponsor:
Sohag University
Conditions:
Telocytes in Umbilical Cord of Pregnancies Complicated by Chronic Hypertension, Gestational Hypertension and Preeclampsia
Eligibility:
FEMALE
Brief Summary
Studying the ultrastructural and immunohistochemical characteristics of Telocytes from umbilical cord vessels wall in PE patients compared to control and its relation to severity of disease whether co...
Detailed Description
Patients fulfilling the eligibility criteria of the current research will be approached prior to delivery. The attending physician will explain the nature of the study and all patients will be asked t...
Eligibility Criteria
Inclusion
- Study group Singleton pregnancies complicated with hypertension undergoing pre-labour CS at gestational age (34+0 to 40+0). These will be divided into 3 groups according to the type of disease either chronic hypertension (Group A), gestational hypertension (Group B) or preeclampsia (Group C).
- Control group Singleton pregnancies undergoing elective pre-labour CS that are otherwise healthy.
Exclusion
- Women with history of medical co-morbidities other than hypertension were excluded from the study. This includes the following: Renal diseases, autoimmune diseases, history of organ transplantation and immunosuppressive therapy, hematological diseases, history of thrombotic events, cardiopulmonary diseases, liver diseases, Acute and chronic inflammatory diseases.
- Pregnancy induced medical disorders like: Gestational thrombocytopenia.
- Multiple pregnancies.
- Abnormal placentation, i.e. Placenta previa and Morbidly adherent placenta.
- Fetal anomalies.
- vaginal deliveries and CS in labour.
Key Trial Info
Start Date :
February 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 30 2023
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT05305339
Start Date
February 1 2022
End Date
April 30 2023
Last Update
March 31 2022
Active Locations (1)
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1
Hatem Awaga
Sohag, Egypt, 82524