Status:

RECRUITING

Early Identification and Prognosis Prediction of Sepsis Through Multiomics

Lead Sponsor:

Yantai Yuhuangding Hospital

Conditions:

Sepsis

Eligibility:

All Genders

18-85 years

Brief Summary

This study aims to integrate multi-omics data and clinical indicators to reveal pathogen-specific molecular patterns in patients with sepsis and establish prognostic prediction models through multiple...

Detailed Description

This study aims to quantify the plasma metabolome, single nucleotide polymorphisms (SNPs) of exons and immunocytokines of septic patients with different pathogen infections and prognostic outcomes. Mu...

Eligibility Criteria

Inclusion

  • Patients with sepsis or septic shock who meet the diagnostic criteria (2016 sepsis 3.0 standard);
  • Age 18~85 years old.

Exclusion

  • ICU stay of the subjects less than 72 hours;
  • Female subjects who are pregnant;
  • The subjects not sure if infected;
  • The subjects performed CPR;
  • The subjects suffer from chronic renal disease;
  • The subjects with incomplete clinical data.

Key Trial Info

Start Date :

January 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

900 Patients enrolled

Trial Details

Trial ID

NCT05305469

Start Date

January 1 2022

End Date

December 31 2025

Last Update

January 24 2024

Active Locations (1)

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Yantai Yuhuangding Hospital

Yantai, Shandong, China, 264000