Status:

RECRUITING

Physical Activity, Knee Joint Loading and Joint Health

Lead Sponsor:

University of Bath

Collaborating Sponsors:

Versus Arthritis

Conditions:

Anterior Cruciate Ligament Injuries

Anterior Cruciate Ligament Rupture

Eligibility:

All Genders

18-39 years

Brief Summary

The purpose of this study is to investigate the association between time spent in moderate to vigorous physical activity and markers of cartilage metabolism in the years following anterior cruciate li...

Detailed Description

Participants attend the laboratory on two or three occasions and wear accelerometers for the 10 days in between the first and second laboratory session. The first laboratory session involves urine sam...

Eligibility Criteria

Inclusion

  • 18-39 years old (i.e., ≥18 and \<40 years old)
  • Had an anterior cruciate ligament injury and reconstruction 1-7 years ago (i.e., ≥1 and ≤7 years ago)
  • Can have sustained damage to meniscus or cartilage, or sustained bone bruising when injured anterior cruciate ligament
  • Can participate regardless of the type of reconstruction surgery and if undergone meniscectomy
  • Completed anterior cruciate ligament reconstruction rehabilitation and either a surgeon, doctor or physiotherapist has provided clearance to participate in physical activity
  • Be able to attend the University of Bath within 2 hours of waking

Exclusion

  • Had another significant knee injury either before, at the same time, or after the anterior cruciate ligament injury (e.g., if they injured another ligament in their knee or had a fracture or dislocation)
  • Injured the anterior cruciate ligament in both knees (bilateral ACL injury)
  • Have/are experiencing a musculoskeletal, cardiovascular, respiratory, immune, metabolic or neurological disease or disorder
  • Under 18 or over 39 (i.e., ≥40) years of age
  • Body Mass Index ≥40 kg/m²
  • Pregnancy
  • Positive responses to the Physical Activity Readiness Questionnaire (aside from any involved knee joint issues)

Key Trial Info

Start Date :

June 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 1 2024

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT05306054

Start Date

June 1 2022

End Date

July 1 2024

Last Update

March 15 2024

Active Locations (1)

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1

University of Bath

Bath, United Kingdom