Status:
COMPLETED
Comparison of Antimicrobial Action of Sodium Hypochlorite and Polyhexamethylene Biguanide as Root Canal Irrigants
Lead Sponsor:
Altamash Institute of Dental Medicine
Conditions:
Irreversible Pulpitis
Eligibility:
All Genders
18-50 years
Phase:
PHASE2
Brief Summary
The aim of this randomized clinical trial is to compare the antibacterial effects of sodium hypochlorite (NaOCl) and Polyhexamethylene biguanide during root canal treatment .
Detailed Description
This study will compare the antibacterial effectiveness of sodium hypochlorite and PHMB, to find out whether PHMB can be used as a substitute to NaOCL. Polyhexamethylene biguanide (PHMB), is a disinfe...
Eligibility Criteria
Inclusion
- • Patients aged 18 to 50 years
- Both male and female patients
- Periodontally healthy teeth as determined by Periodontal Probing
- Patients with non-vital necrotic pulps as determined by Cold Test
- Patients with acute apical periodontitis determined by history and clinical examination
- Clinical Findings:
- Visual: Carious tooth decay Occlusion: Hyperocclusion Pulp vitality test: Negative Periapical radiograph: Caries involving pulp space and PDL widening Percussion Test: Positive Palpation Test: Negative
- • Single rooted teeth as determined radiographically
Exclusion
- • Multirooted teeth
- Teeth undergoing Re-endo treatments
- Teeth with root fractures and/ non restorable determined by clinical and radiographic examination
- Patients receiving antibiotic treatment in the past 3 months determined by history
- Patient with Diabetes determined by history
- Patient with history of smoking
Key Trial Info
Start Date :
June 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 30 2022
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05306431
Start Date
June 1 2022
End Date
November 30 2022
Last Update
February 21 2023
Active Locations (1)
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1
Hira Danish
Karachi, Sindh, Pakistan, 75500