Status:
RECRUITING
Exercise in Extended Oncogene Addicted Lung Cancer in Active Treatment
Lead Sponsor:
AUSL Romagna Rimini
Collaborating Sponsors:
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Conditions:
Non-Small Cell Lung Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This is an interventional, non-pharmacologic, randomized controlled study evaluating the impact on quality of life of a personalized exercise program in oncogene addicted lung cancer patients undergoi...
Detailed Description
This is an interventional, non pharmacological, randomized controlled trial evaluating the impact on quality of life of a personalized exercise program in oncogene addicted lung cancer patients underg...
Eligibility Criteria
Inclusion
- Age 18 years or older
- Willingness to provide written informed consent.
- Life expectancy \>12 weeks.
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 1.
- Body massa index \> 18.
- Oncogene-addicted (EGFR, ALK, ROS1, RET, BRAF) stage IV or III b not suitable for local treatment receiving first- or second-line systemic treatment (palliative radiotherapy and prior chemotherapy allowed). Patients undergoing treatment in clinical trials are excluded.
Exclusion
- Inability to walk.
- Immobility for more than 3 days before study enrollment.
- Previously untreated (non-irradiated or non-resected) symptomatic brain metastases.
- Severe cardiac impairment (e.g. cardiac insufficiency New York Heart Association (NYHA) \> III, myocardial infarction within the last three months, severe cardiac arrhythmias, high grade aortic stenosis).
- Severe respiratory failure.
- Uncontrolled pain.
- Bone metastasis inducing increased risk of pathological fractures.
Key Trial Info
Start Date :
April 4 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2026
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT05306652
Start Date
April 4 2022
End Date
June 1 2026
Last Update
May 31 2023
Active Locations (1)
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1
S.Maria delle Croci Hospital, Oncology Unit
Ravenna, Italy