Status:
COMPLETED
COVID-19 and Brain: Cognition and Mental Health
Lead Sponsor:
University of Barcelona
Collaborating Sponsors:
Consorci Sanitari de Terrassa
Universitat Politècnica de Catalunya
Conditions:
COVID-19
Eligibility:
All Genders
18-65 years
Brief Summary
The main goal of DIANA is to investigate the potential discriminative power of multimodal biomarkers in COVID adverse outcomes. The study of the neuropathological underlying mechanisms in COVID from a...
Detailed Description
DIANA project is an observational, descriptive, and cross-sectional study in which participants will not be randomized. Case people (adult survivors of severe COVID-19 N=134) will compare to healthy a...
Eligibility Criteria
Inclusion
- Post-COVID Group:
- Confirmed diagnosis of COVID-19 according to WHO interim with signs and symptoms of the severe disease during the acute phase
- Presence of cognitive complaints after COVID-19 diagnosis
- Participants have to be discharged from the hospital at least three months before inclusion
- Accept to take part in the study and sign the informed consent according to the Declaration of Helsinki
Exclusion
- Participants have symptoms of delirium according to Delirium Rating Scale-revised 98
- Established diagnosis before COVID-19 disease of psychiatric, neurological, neurodevelopmental disorder or systemic pathologies are known to cause cognitive deficits
- Motor or sensory alterations that impede the neuropsychological examination
- Participants with a metal prosthesis (for MRI studies)
- Subjects suffering from claustrophobia or requiring sedation due to high anxiety (for MRI studies)
- Healthy Adult Control group
- Inclusion Criteria
- Healthy people who have not had COVID-19
- Accept to take part in the study and sign the informed consent according to the Declaration of Helsinki
- Exclusion criteria: the same as COVID-19 survivors
Key Trial Info
Start Date :
May 14 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2022
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT05307549
Start Date
May 14 2021
End Date
December 31 2022
Last Update
May 30 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Barcelona
Barcelona, Spain, 08036