Status:
UNKNOWN
PET - PEEP by EIT for Acute Respiratory Distress Syndrome Trial
Lead Sponsor:
Peking Union Medical College Hospital
Conditions:
ARDS, Human
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
This study is a multicentric randomized controlled study.The objective of this study is to compare the prognosis of patients with ARDS between EIT-oriented individualized PEEP and traditional lower PE...
Eligibility Criteria
Inclusion
- Intubated, mechanically ventilated patients with diagnosis of ARDS according to ARDS Berlin standard by attending doctor
Exclusion
- Age \< 18 years old and \> 90 years old;
- Pregnancy;
- EIT contradictions (presence of pacemaker or automatic implantable cardioverter defibrillator);
- Severe intracranial hypertension;
- Pneumothorax, pneumomediastinum, subcutaneous emphysema or at high-risk for pneumothorax (e.g., pneumatocele, interstitial lung disease);
- Unstable hemodynamic status intorerable to lung recruitment and PEEP titration, judged by an attending intensivist; (This may be a transient criterion, since patients meeting this criterion might be included later if hemodynamics improves)
- End status of disease;
- Patients or their families refused to participate in the study
Key Trial Info
Start Date :
April 10 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 10 2025
Estimated Enrollment :
680 Patients enrolled
Trial Details
Trial ID
NCT05307913
Start Date
April 10 2022
End Date
April 10 2025
Last Update
April 28 2022
Active Locations (1)
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1
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China, 100730