Status:
COMPLETED
Musical Engagement of Brain LObes in Alzheimer's Disease Patients StudY
Lead Sponsor:
Medical University of South Carolina
Collaborating Sponsors:
National Endowment for the Arts, United States
American Association of Retired Persons
Conditions:
Alzheimer Disease
Dementia
Eligibility:
All Genders
55-90 years
Phase:
NA
Brief Summary
This is a randomized, cross-over study to measure global and clinical impact and level of arousal in subjects suffering from moderate to severe Alzheimer's disease when exposed to emotionally impactfu...
Detailed Description
In partnership with the study partner (a person who spends 10 hours or more a week with the subject and can reliably report on the subject's condition), three tunes will be chosen for the purposes of ...
Eligibility Criteria
Inclusion
- Provision of signed and dated informed consent form
- Person of any sex/gender aged between 55 and 90
- Stated willingness to comply with all study procedures and availability for the duration of the study
- In the opinion of the investigator, has an informant able and willing to provide accurate information about the participant (may be paid or unpaid caregiver)
- Suffer from moderate to severe Alzheimer's disease as established by the study team using the National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer's Disease and Related Disorders Association (NINCDS-ADRDA) Alzheimer's Criteria for possible and probable Alzheimer's Disease
- Diagnosis of Alzheimer's disease or other type of dementia as defined by the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V)
- Mini Mental State Examination (MMSE) score of 5-20
- Subject is reported by the study partner to be able to listen to a minimum of 10 minutes of music and a sound in an uninterrupted manner.
Exclusion
- Suffer from severe hearing impairment as reported by the informant
- Presence of neuropsychiatric symptoms of dementia as determined by clinical observation by the Principal Investigator, including history of agitation and/or combative behavior.
- Individuals who score ≥ 12 seconds on the Timed Up and Go (TUG) Test.
Key Trial Info
Start Date :
May 11 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 15 2024
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT05309369
Start Date
May 11 2022
End Date
March 15 2024
Last Update
September 9 2025
Active Locations (1)
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1
Medical University of South Carolina
Charleston, South Carolina, United States, 29425