Status:
COMPLETED
Early Detection of Primary Antibody Deficiencies in Primary Care Facilities by an Algorithm Driven Selection of Serologic Testing in Individuals at Risk.
Lead Sponsor:
UMC Utrecht
Conditions:
Primary Antibody Deficiencies
Eligibility:
All Genders
12-70 years
Brief Summary
Rationale: Primary antibody deficiencies (PAD) encompass a group of rare heterogeneous diseases. The clinical presentation may vary widely, including infectious and autoimmune symptoms and increased r...
Eligibility Criteria
Inclusion
- Age between 12 and 70 years
- A total algorithm score that is within the highest 0.66% of the algorithm scores within a single general practitioner's clinic
- Signed informed consent
- Did not meet exclusion criteria during manual evaluation of the health care record
Exclusion
- Secondary causes of immunodeficiency as registered by ICPC codes for: multiple myeloma, HIV-infection, anorexia nervosa, bulimia, cystic fibrosis.
- The presence of one of the following during manual screening of the health care record: nephrotic syndrome, current systemic chemotherapy and stage 3-4 liver cirrhosis will be excluded. This could not be done by the algorithm as there is no ICPC code available.
Key Trial Info
Start Date :
May 24 2022
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 20 2023
Estimated Enrollment :
104 Patients enrolled
Trial Details
Trial ID
NCT05310604
Start Date
May 24 2022
End Date
February 20 2023
Last Update
February 21 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Medical Center Utrecht
Utrecht, Netherlands