Status:
COMPLETED
Cytisine and E-cigarettes With Supportive Text-messaging for Smoking Cessation (Cess@Tion)
Lead Sponsor:
University of Auckland, New Zealand
Conditions:
Smoking Cessation
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
This research focuses on maximizing the benefits of proven smoking cessation interventions to support people who smoke to quit, as part of the strategy to help New Zealand become smoke-free. A large, ...
Detailed Description
Aim: To evaluate the effectiveness, safety, and acceptability of combination treatment (cytisine plus nicotine e-cigarettes) compared to monotherapy (cytisine only or nicotine e-cigarettes only) on s...
Eligibility Criteria
Inclusion
- Daily smokers who live in New Zealand
- Aged ≥18 years
- Motivated to quit smoking within the next two weeks
- Able to provide consent
- Have daily access to a mobile telephone that can text
- Have access to the internet via a computer or smart phone
- Are willing to use cytisine or an e-cigarette or both products to help quit smoking
Exclusion
- Have another person in their household currently enrolled in the study
- Are pregnant/breastfeeding, or are women trying to become pregnant in the next three months
- Are currently using smoking cessation medication (including using e-cigarettes daily for the last month)
- Are enrolled in another cessation programme/trial
- Have a known hypersensitivity to cytisine or nicotine e-cigarettes
- Self-report moderate/severe renal impairment
- Are undergoing treatment for active/latent tuberculosis
- Have experienced a myocardial infarction, stroke, or severe angina within the previous two weeks
- Have uncontrolled high blood pressure (\>150 mmHg systolic, \>100 mmHg diastolic)
- Have a history of seizures / epilepsy
- Have a strong preference to use or not to use cytisine and/or e-cigarettes in their quit attempt.
- Have a history of severe allergy and/or poorly controlled asthma.
Key Trial Info
Start Date :
May 5 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 26 2024
Estimated Enrollment :
807 Patients enrolled
Trial Details
Trial ID
NCT05311085
Start Date
May 5 2022
End Date
July 26 2024
Last Update
December 19 2024
Active Locations (1)
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1
National Institute for Health Innovation, School of Population Health, Faculty of Medical and Health Sciences, University of Auckland
Auckland, New Zealand, 1142