Status:

COMPLETED

An RCT of NBI vs. White Light Guided Endobronchial Biopsy in Suspected Sarcoidosis

Lead Sponsor:

Post Graduate Institute of Medical Education and Research, Chandigarh

Conditions:

Sarcoidosis, Pulmonary

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

In the diagnosis of patients with sarcoidosis, there is paucity of literature on the diagnostic yield of the endobronchial biopsies obtained with narrow band imaging (NBI) bronchoscopy. The present st...

Detailed Description

The present study will be a randomized controlled trial. It will be performed in the Bronchoscopy suite of the Department of Pulmonary Medicine, PGIMER. Subjects meeting the selection criteria will be...

Eligibility Criteria

Inclusion

  • Age more than 18 years.
  • Clinical presentation and radiological findings (enlarged hilar and or mediastinal lymph nodes \>10 mm \[short axis\], and/or perilymphatic nodules or peribronchovascular thickening on computed tomography \[CT\] chest) suggesting sarcoidosis.
  • Willing to give informed consent.

Exclusion

  • Hemodynamic instability (systolic BP \<100 mm Hg).
  • Pregnancy.
  • Treatment with systemic glucocorticoids for more than three weeks in the preceding three months.
  • Diagnosis of sarcoidosis possible with another minimally invasive technique such as skin biopsy or peripheral lymph node biopsy.

Key Trial Info

Start Date :

January 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 15 2023

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT05311150

Start Date

January 1 2022

End Date

February 15 2023

Last Update

March 29 2023

Active Locations (1)

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Postgraduate Institute of Medical Education and Research

Chandigarh, India, 160012