Status:
RECRUITING
Development of a Battery of Audiological Tests for the Precision Diagnosis of Age-related Hearing Loss
Lead Sponsor:
Institut Pasteur
Collaborating Sponsors:
CEntre de Recherche et d'Innovation en Audiologie Humaine
Laboratoire de correction auditive
Conditions:
Presbyacusis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Age-related hearing loss, or presbycusis, is caused by many genetic and environmental factors. Its prevalence poses a public health challenge of early identification and effective hearing aid treatmen...
Detailed Description
The AUDIOGENAGE project is a multi-center, non-invasive case-control study conducted by CERIAH (CEntre de Recherche et d'Innovation en Human Audiology) and LCA (Laboratory de correction auditive) in 7...
Eligibility Criteria
Inclusion
- For all participants:
- Be over the age of 18,
- Be affiliated to a social security system,
- Have a good command of the French language (oral and written).
- For the group of participants with anticipated presbycusis:
- Over the age of 40, having a hearing aid recipient or coming for a first hearing aid recipient
- Between 18 and 40, having a hearing aid recipient, coming for a first hearing aid recipient or declare a progressive genetic birth defect
- For healthy volunteers:
- \- Have no known hearing loss.
Exclusion
- Report having been chronically exposed to loud sounds.
- Have a history of ototoxic substances,
- To have sequelae of ear infections and/or a history of ENT disease that permanently affects hearing or balance,
- Have an ethnic origin for which the Pasteur Institute does not have information on the frequency of variants of the genes studied.
- Have type II diabetes,
- Have a neurological or psychiatric condition that interferes with comprehension or ability to move,
- Be under guardianship,
- Be deprived of liberty by judicial or administrative decision, or be subject to legal protection,
- Not being subject to a social security system,
- Taking narcotic substances, alcohol or medication that diminishes cognitive abilities.
Key Trial Info
Start Date :
July 28 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2030
Estimated Enrollment :
700 Patients enrolled
Trial Details
Trial ID
NCT05312983
Start Date
July 28 2022
End Date
December 31 2030
Last Update
March 3 2025
Active Locations (2)
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1
Laboratoire de correction auditive
Paris, France, 75001
2
CEntre de Recherche et d'Innovation en Audiologie Humaine
Paris, France, 75012