Status:
UNKNOWN
Identification of Non-motor Brain Areas Involved in Upper Limb Motor Recovery After Stroke
Lead Sponsor:
University Hospital, Montpellier
Collaborating Sponsors:
Centre Hospitalier Universitaire de Nīmes
Euromov, Université Montpellier
Conditions:
Upper Limb Ischemia
Stroke
Eligibility:
All Genders
18-85 years
Brief Summary
Why: Upper-limb recovery post-stroke is challenging. Rehabilitation, aiming to induce plasticity takes an important place in patients' treatment. The last years, non-invasive brain stimulation of the ...
Detailed Description
Patients' brain activity and connectivity during an elbow flexion/extension task will be evaluated at 2 weeks (V0), 3 months (V1) and 6 months (V2) post-stroke. Between V0 and V1, patients will receiv...
Eligibility Criteria
Inclusion
- Inclusion Criteria patients post-stroke:
- 18-85 yrs,
- First ever ischemic stroke of the middle cerebral artery,
- Initial severe motor deficit (fugl-Upper limb assessment score \<30/66),
- Written consent.
- Exclusion criteria patients post-stroke:
- The presence of secondary neurological or psychiatric deficits,
- Strong hemineglect (bell-test);
- Aphasie \>3/5 on the Boston scale,
- Bilateral stroke,
- Hemorraghic stroke,
- MRI contra-indications,
- Pregnancy/breastfeading,
- Patient under curatele,
- Medical urgency.
- Inclusion criteria healthy subjects:
- Age matching (+/- 5 yrs),
- Sexe matching,
- Written consent.
- Exclusion criteria healthy subjets:
- Neurological or psychological deficits;
- MRI contra-indations;
- Pregnancy/breastfeeding,
- Personunder curatele.
Exclusion
Key Trial Info
Start Date :
February 7 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2024
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT05313776
Start Date
February 7 2022
End Date
June 1 2024
Last Update
March 9 2023
Active Locations (1)
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1
Montpellier University Hospital
Montpellier, France, 34090