Status:

RECRUITING

Safety and Efficacy of Corneal Cross-linking in Subjects With Keratoconus

Lead Sponsor:

Glaukos Corporation

Conditions:

Progressive Keratoconus

Eligibility:

All Genders

18-55 years

Phase:

PHASE1

PHASE2

Brief Summary

Clinical Trial to Evaluate the Safety and Efficacy of Corneal Cross-linking in Subjects with Keratoconus.

Detailed Description

This is a a dose ranging, multi-center, sham-controlled study to evaluate the safety and efficacy of epithelium-on corneal collagen cross-linking. The study will evaluate safety and efficacy in subjec...

Eligibility Criteria

Inclusion

  • Provide written informed consent
  • Ability to hold gaze sufficiently stable for study testing
  • Willingness and ability to follow all instructions and comply with schedule for follow-up visits
  • Have a diagnosis of keratoconus

Exclusion

  • Known allergy or sensitivity to the test articles or components
  • Any disease causing abnormal topography other than keratoconus
  • Prior or current ocular condition (other than keratoconus) in the study eye that may predispose the eye for future complications

Key Trial Info

Start Date :

March 8 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2026

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT05314738

Start Date

March 8 2022

End Date

February 1 2026

Last Update

July 8 2024

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Glaukos Investigative Site

Dothan, Alabama, United States, 36301

2

Glaukos Investigative Site

Teaneck, New Jersey, United States, 07666

3

Glaukos Investigative Site

Westerville, Ohio, United States, 43082

Safety and Efficacy of Corneal Cross-linking in Subjects With Keratoconus | DecenTrialz