Status:
RECRUITING
Sitting Interruption and Whole-body Cardiovascular Health
Lead Sponsor:
University of North Carolina, Chapel Hill
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Sedentary Behavior
Sedentary Time
Eligibility:
All Genders
30-60 years
Phase:
NA
Brief Summary
There is strong evidence for the association between sedentary behaviors and cardiovascular diseases such as coronary heart disease and stroke. However, the public currently has no clear guidance on h...
Detailed Description
Sedentary behaviors (SB) are biologically distinct but understudied heart disease risk factors. National and international agencies have concluded that the level of evidence for an overall and dose-re...
Eligibility Criteria
Inclusion
- Aged between 30-60 years
- Insufficiently active: self-reported exercise \<90 minutes per week for the past 3 months
- Sedentary: self-reported sitting \>8 hours per day
- Self-reported ability to walk 4 blocks and climb 2 flights of stairs
- Possession of cellular phone able to receive text messages
Exclusion
- Use of assisted-walking devices
- Comorbid condition that would limit the ability to reduce sedentary behavior (e.g., musculoskeletal condition, current chemotherapy)
- Plans for major surgery within next 3 months
- Recent history (\<1 year) of ischemic heart disease, chronic heart failure, stroke, or chronic kidney disease
- Recent (\< 1 year) or planned bariatric surgery
- Systolic blood pressure ≥160 mmHg or diastolic blood pressure ≥100 mmHg
- Current or recent (within last 6 months) pregnancy; current or recent (within last 3 months) breastfeeding
- Morbidly obesity (BMI \>40 kg/m\^2) or underweight (BMI \<18.5 kg/m\^2)
- Use of anti-hypertensive drugs
- Use of glucose-controlling medication
- Heavy alcohol consumption (\>15 drinks per week)
Key Trial Info
Start Date :
August 15 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 28 2026
Estimated Enrollment :
56 Patients enrolled
Trial Details
Trial ID
NCT05316571
Start Date
August 15 2022
End Date
February 28 2026
Last Update
January 10 2025
Active Locations (1)
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1
University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, United States, 27599